Date | Version | Revision |
Feb 20, 2002 | 1.0 | MemExp 1.0 released [1]. |
Mar 15, 2002 | 1.1 | Fixed bug causing crash when NDIST=1 and NBASLN>0 |
Mar 27, 2002 | 1.2 | Fixed bug involving INSIG = 0.
Fixed bug involving first time value = 0. Improved y-axis numbering in PostScript output. Modified plotting of autocorrelation of residuals (x values are now equally spaced). |
Nov 1, 2002 | 2.0 | Improved the differential blurring of f into F for kinetics involving overlapping exponential and distributed phases [2].
More than 9 rows of plots in PostScript output allowed (see PLOTS). Additional improvements to graphics. Additional normalization options (see D0OPT). The required input has changed slightly from version 1.2. Discarded input parameters: SYNDAT, NFUNC0. New input parameters: D0OPT, EXPMN2, PLOTS, FSCALE, FIXSUM, WRNORM, SPIKE3, DAREA, NSPIKE, MNSPK, HOWSPK, DARSPK, FWSPK, DCHI2C |
July 22, 2004 | 3.0 | Poisson noise treated
rigorously. Deconvolution of measured instrument response supported. Light-scattering correction added.
The required input has changed slightly from version 2.0. IGNORE is now an integer (0, 1, or 2). New input parameters: RESPON, EPSIRF, IRSMOTH, LTSCAT. |
Jan 23, 2007 | 3.0 | Executable built for Mac OS X. |
June 13, 2012 | 4.0 | New, easy-to-use simple and auto modes.
New option for adapting prior model from kinetics (setting IBIGF=3) can suppress artifacts and improve peak positions
in the lifetime distribution. See: P.J. Steinbach, Filtering artifacts from lifetime distributions when maximizing entropy using a bootstrapped model, Analytical Biochemistry 427 (2012) 102-105. |
Nov 25, 2013 | 4.1 | Fixed problems reading IRF in invert and analysis modes. |
Oct 29, 2014 | 4.2 | Better initial parameters for simple mode. Fixed floating-point exception when pre-fitting baseline (TBASLN>0). |
Oct 26, 2017 | 5.0 | Estimation of zero-time-shift parameter when deconvolving an IRF. Automated fits by discrete exponentials now initialized based on recommended MEM fit. |
Jan 31, 2020 | 6.0 | The convolution of the decay with the instrument response function (IRF) is performed using a cubic approximation of the count function for the IRF (Z. Bajzer et al, Biophys J. 81 2001 1765-1775). Additional parameters on command line increase user control in simple mode. |