DateVersionRevision
Feb 20, 20021.0MemExp 1.0 released [1].
Mar 15, 20021.1Fixed bug causing crash when NDIST=1 and NBASLN>0
Mar 27, 2002



1.2



Fixed bug involving INSIG = 0.
Fixed bug involving first time value = 0.
Improved y-axis numbering in PostScript output.
Modified plotting of autocorrelation of residuals (x values are now equally spaced).
Nov 1, 2002




2.0




Improved the differential blurring of f into F for kinetics involving overlapping exponential and distributed phases [2].
More than 9 rows of plots in PostScript output allowed (see PLOTS). Additional improvements to graphics.
Additional normalization options (see D0OPT). The required input has changed slightly from version 1.2.
Discarded input parameters: SYNDAT, NFUNC0. New input parameters: D0OPT, EXPMN2, PLOTS, FSCALE, FIXSUM, WRNORM,
SPIKE3, DAREA, NSPIKE, MNSPK, HOWSPK, DARSPK, FWSPK, DCHI2C
July 22, 2004


3.0


Poisson noise treated rigorously. Deconvolution of measured instrument response supported. Light-scattering correction added.
The required input has changed slightly from version 2.0.
IGNORE is now an integer (0, 1, or 2). New input parameters: RESPON, EPSIRF, IRSMOTH, LTSCAT.
Jan 23, 20073.0Executable built for Mac OS X.
June 13, 20124.0New, easy-to-use simple and auto modes. New option for adapting prior model from kinetics (setting IBIGF=3) can suppress artifacts and improve peak positions in the lifetime distribution.
See:
P.J. Steinbach, Filtering artifacts from lifetime distributions when maximizing entropy using a bootstrapped model, Analytical Biochemistry 427 (2012) 102-105.
Nov 25, 20134.1Fixed problems reading IRF in invert and analysis modes.
Oct 29, 20144.2Better initial parameters for simple mode. Fixed floating-point exception when pre-fitting baseline (TBASLN>0).
Oct 26, 20175.0 Estimation of zero-time-shift parameter when deconvolving an IRF. Automated fits by discrete exponentials now initialized based on recommended MEM fit.
Jan 31, 20206.0 The convolution of the decay with the instrument response function (IRF) is performed using a cubic approximation of the count function for the IRF (Z. Bajzer et al, Biophys J. 81 2001 1765-1775). Additional parameters on command line increase user control in simple mode.